Rabies is a virus that affects the brain and spinal cord of all mammals, including dogs, cats, and humans. Though preventable, there is a good reason that the word rabies evokes fear in people. The disease has been reported everywhere throughout the world except for Australia and Antarctica. Every year, rabies causes the deaths of more than 50,000 humans and millions of animals worldwide. Once the symptoms appear, the disease often results in a fatality. Although most animals are affected by this disease, this article focuses on rabies in dogs, the symptoms, precautions, and management.